1-samuel 25:22

So and more also do God - Nothing can justify this part of David's conduct. Whatever his provocation might have been, he had suffered, properly speaking, no wrongs; and his resolution to cut off a whole innocent family, because Nabal had acted ungenerously towards him, was abominable and cruel, not to say diabolic. He who attempts to vindicate this conduct of David is, at least constructively, a foe to God and truth. David himself condemns this most rash and unwarrantable conduct, and thanks God for having prevented him from doing this evil, 1 Samuel 25:32, etc.

Any that pisseth against the wall - This expression certainly means either men or dogs, and should be thus translated, if I leave, any male; and this will answer both to men and dogs, and the offensive mode of expression be avoided. I will not enter farther into the subject: Bochart and Calmet have done enough, and more than enough; and in the plainest language too.

The concluding phrase denotes the utter destruction of a family, and is rightly explained to mean "every male," perhaps with the idea, "down to the very meanest member of the household."

25:22 Enemies of David - That is, unto David himself. But because it might seem ominous to curse himself, therefore instead of David, he mentions David's enemies. But is this the voice of David? Can he speak so unadvisedly with his lips? Has he been so long in the school of affliction, and learned no more patience therein? Lord, what is man?And what need have we to pray, lead us not into temptation.